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MLB prediction

Cleveland Guardians vs Boston Red Sox prediction

Final · Cleveland Guardians 3, Boston Red Sox 2
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Last line before the game

MoneylineCleveland Guardians +107 · Boston Red Sox -130
SpreadBoston Red Sox -1.5
Total6.5

Latest line across Bovada, FanDuel.

Matchup

Cleveland Guardians visited Boston Red Sox at Fenway Park on Tuesday, September 22, 2026 at 5:45 PM CT.

On the moneyline the market favors Boston Red Sox at -130, with Cleveland Guardians at +107 — once the bookmaker margin is removed, that prices Boston Red Sox at about 54% to win.

The spread has Boston Red Sox at -1.5 and Cleveland Guardians at +1.5.

The game total is 6.5.

Final: Cleveland Guardians 3, Boston Red Sox 2. Cleveland Guardians won.

Our MLB record

All-time280-200 (58%) · 1 push
This season (since Feb 1, 2026)280-200 (58%)
Last 14 daysno settled picks

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