Detroit Lions vs Arizona Cardinals prediction
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Last line before the game
| Moneyline | Detroit Lions -245 · Arizona Cardinals +200 |
| Spread | Arizona Cardinals +5 |
| Total | 54.5 |
Latest line across Bovada, FanDuel.
Matchup
Detroit Lions visited Arizona Cardinals at State Farm Stadium on Sunday, October 11, 2026 at 3:25 PM CT, on Fox.
Detroit Lions came in at 3-2; Arizona Cardinals were 1-4.
On the moneyline the market favors Detroit Lions at -245, with Arizona Cardinals at +200 — once the bookmaker margin is removed, that prices Detroit Lions at about 68% to win.
The spread has Arizona Cardinals at +5 and Detroit Lions at -5.
That line has moved from Arizona Cardinals +5.5 when we first tracked it.
The game total is 54.5.
Final: Detroit Lions 45, Arizona Cardinals 21. Detroit Lions won.
Our NFL record
| All-time | 8-9 (47%) |
| This season (since Aug 1, 2026) | 8-9 (47%) |
| Last 14 days | 1-4 (20%) |
Win rate and record of every NFL pick sent to members on the current model, graded after the final whistle. Full track record →