New England Patriots vs Buffalo Bills prediction
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Last line before the game
| Moneyline | New England Patriots +100 · Buffalo Bills -320 |
| Spread | Buffalo Bills -7 |
| Total | 50 |
Latest line across Bovada, FanDuel.
Matchup
New England Patriots visited Buffalo Bills at Highmark Stadium on Sunday, October 4, 2026 at 12:00 PM CT, on CBS.
New England Patriots came in at 2-2; Buffalo Bills were 3-1.
On the moneyline the market favors Buffalo Bills at -320, with New England Patriots at +100 — once the bookmaker margin is removed, that prices Buffalo Bills at about 60% to win.
The spread has Buffalo Bills at -7 and New England Patriots at +7.
That line has moved from Buffalo Bills -6.5 when we first tracked it.
The game total is 50.
The total has moved up from 48.5 since we first tracked it.
Final: New England Patriots 29, Buffalo Bills 26. New England Patriots won.
Our NFL record
| All-time | 8-9 (47%) |
| This season (since Aug 1, 2026) | 8-9 (47%) |
| Last 14 days | 1-4 (20%) |
Win rate and record of every NFL pick sent to members on the current model, graded after the final whistle. Full track record →