San Francisco 49ers vs Los Angeles Rams prediction
Free pick
A free pick — the same play, at the line it was posted at.
Every graded pick, player props and the confidence behind each one, before the games start.
Last line before the game
| Moneyline | San Francisco 49ers +166 · Los Angeles Rams -200 |
| Spread | Los Angeles Rams -3.5 |
| Total | 48 |
Latest line across Bovada, FanDuel.
Matchup
San Francisco 49ers visited Los Angeles Rams at Melbourne Cricket Ground on Thursday, September 10, 2026 at 7:35 PM CT, on Netflix.
San Francisco 49ers came in at 1-0; Los Angeles Rams were 0-1.
On the moneyline the market favors Los Angeles Rams at -200, with San Francisco 49ers at +166 — once the bookmaker margin is removed, that prices Los Angeles Rams at about 64% to win.
The spread has Los Angeles Rams at -3.5 and San Francisco 49ers at +3.5.
The game total is 48.
The total has moved down from 48.5 since we first tracked it.
Final: San Francisco 49ers 27, Los Angeles Rams 7. San Francisco 49ers won.
Our NFL record
| All-time | 8-9 (47%) |
| This season (since Aug 1, 2026) | 8-9 (47%) |
| Last 14 days | 1-4 (20%) |
Win rate and record of every NFL pick sent to members on the current model, graded after the final whistle. Full track record →